ParkinsonCanadaV1, Main, Exploration, bibRecord, 002912

Practice Parameter:Diagnosis and prognosis of new onset Parkinson disease (an evidence-based review) : Report of the quality standards subcommittee of the american academy of neurology

Identifieur interne : 002912 ( Main/Exploration ); précédent : 002911; suivant : 002913

Practice Parameter:Diagnosis and prognosis of new onset Parkinson disease (an evidence-based review) : Report of the quality standards subcommittee of the american academy of neurology

Auteurs : O. Suchowersky [Canada] ; S. Reich [États-Unis] ; J. Perlmutter [États-Unis] ; T. Zesiewicz [États-Unis] ; G. Gronseth [États-Unis] ; W. J. Weiner [États-Unis]

Source :

Neurology [ 0028-3878 ] ; 2006.

RBID : Pascal:06-0225666

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Parkinson maladie, Diagnostic, Pronostic, Américain, Neurologie.
Wicri :
- topic : Neurologie.

English descriptors

KwdEn :
- American, Diagnosis, Nervous system diseases, Neurology, Parkinson disease, Prognosis.

Abstract

Objective: To define key issues in the diagnosis of Parkinson disease (PD), to define features influencing progression, and to make evidence-based recommendations. Two clinical questions were identified: 1) Which clinical features and diagnostic modalities distinguish PD from other parkinsonian syndromes? 2) Which clinical features predict rate of disease progression? Methods: Systematic review of the literature was completed. Articles were classified according to a four-tiered level of evidence scheme. Recommendations were based on the evidence. Results and Conclusions: 1. Early falls, poor response to levodopa, symmetry of motor manifestations, lack of tremor, and early autonomic dysfunction are probably useful in distinguishing other parkinsonian syndromes from Parkinson disease (PD). 2. Levodopa or apomorphine challenge and olfactory testing are probably useful in distinguishing PD from other parkinsonian syndromes. 3. Predictive factors for more rapid motor progression, nursing home placement, and shorter survival time include older age at onset of PD, associated comorbidities, presentation with rigidity and bradykinesia, and decreased dopamine responsiveness. Future research into methods for earlier and more accurate diagnosis of the disease and identification and clarification of predictive factors of rapid disease progression is warranted.

Affiliations:

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 000843
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to stream PascalFrancis, to step Checkpoint: 000706
to stream Main, to step Merge: 002C04
to stream Main, to step Curation: 002912

Le document en format XML

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<front><div type="abstract" xml:lang="en">Objective: To define key issues in the diagnosis of Parkinson disease (PD), to define features influencing progression, and to make evidence-based recommendations. Two clinical questions were identified: 1) Which clinical features and diagnostic modalities distinguish PD from other parkinsonian syndromes? 2) Which clinical features predict rate of disease progression? Methods: Systematic review of the literature was completed. Articles were classified according to a four-tiered level of evidence scheme. Recommendations were based on the evidence. Results and Conclusions: 1. Early falls, poor response to levodopa, symmetry of motor manifestations, lack of tremor, and early autonomic dysfunction are probably useful in distinguishing other parkinsonian syndromes from Parkinson disease (PD). 2. Levodopa or apomorphine challenge and olfactory testing are probably useful in distinguishing PD from other parkinsonian syndromes. 3. Predictive factors for more rapid motor progression, nursing home placement, and shorter survival time include older age at onset of PD, associated comorbidities, presentation with rigidity and bradykinesia, and decreased dopamine responsiveness. Future research into methods for earlier and more accurate diagnosis of the disease and identification and clarification of predictive factors of rapid disease progression is warranted.</div>
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	La maladie de Parkinson au Canada (serveur d'exploration)
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La maladie de Parkinson au Canada (serveur d'exploration)

Practice Parameter:Diagnosis and prognosis of new onset Parkinson disease (an evidence-based review) : Report of the quality standards subcommittee of the american academy of neurology

Practice Parameter:Diagnosis and prognosis of new onset Parkinson disease (an evidence-based review) : Report of the quality standards subcommittee of the american academy of neurology

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri